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MAPK-pathway alterations

Showing 1 - 25 of 5,467
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Advanced Solid Tumors Harboring MAPK Pathway Alterations Trial in Shandong (QLH11906)

Recruiting
  • Advanced Solid Tumors Harboring MAPK Pathway Alterations
  • Shandong, China
    Shandong Cancer Hospital
Aug 3, 2022

Advanced Cancer, Metastatic Cancer, Solid Tumor Trial in United States (JZP815)

Recruiting
  • Advanced Cancer
  • +2 more
  • Denver, Colorado
  • +4 more
Jan 10, 2023

NSCLC, Ovarian Cancer, Melanoma Trial in Worldwide (LXH254, PDR001)

Terminated
  • NSCLC
  • +3 more
  • Boston, Massachusetts
  • +17 more
Dec 20, 2022

Refractory Cancer, CNS Tumors, CNS Tumor, Adult Trial in Atlanta, New York (Avutometinib)

Recruiting
  • Refractory Cancer
  • +14 more
  • Atlanta, Georgia
  • +1 more
Oct 23, 2023

Advanced Solid Tumors With MAPK Pathway Mutations Trial in Nedlands (D3S-002)

Not yet recruiting
  • Advanced Solid Tumors With MAPK Pathway Mutations
  • Nedlands, Western Australia, Australia
    D3 Bio Investigative Site
May 24, 2023

Recurrent Biliary Tract Carcinoma, Recurrent Distal Bile Duct Adenocarcinoma, Recurrent Gallbladder Carcinoma Trial

Not yet recruiting
  • Recurrent Biliary Tract Carcinoma
  • +13 more
  • (no location specified)
Nov 8, 2022

Solid Tumor, Advanced Solid Tumor, Non Small Cell Lung Cancer Trial in Denver, Nashville, Fairfax (MRTX0902, MRTX849)

Recruiting
  • Solid Tumor
  • +3 more
  • Denver, Colorado
  • +2 more
Dec 19, 2022

Pancreatic Ductal Adenocarcinoma, NSCLC, Colorectal Cancer Trial in United States (DCC-3116, Trametinib, Binimetinib)

Recruiting
  • Pancreatic Ductal Adenocarcinoma
  • +5 more
  • Boston, Massachusetts
  • +4 more
May 25, 2022

Low-grade Glioma, Plexiform Neurofibroma, CNS Glioma Trial in Canada (Trametinib)

Active, not recruiting
  • Low-grade Glioma
  • +2 more
  • Calgary, Alberta, Canada
  • +6 more
Oct 25, 2022

Pancreatic Cancer, Small Bowel Cancer, Colorectal Cancer Trial in United States (Ulixertinib (BVD-523))

Available
  • Pancreatic Cancer
  • +20 more
  • Ulixertinib (BVD-523)
  • Birmingham, Alabama
  • +25 more
Nov 4, 2022

Acute Myeloid Leukemia Trial in United States (ERAS-007, ERAS-601, Gilteritinib)

Withdrawn
  • Acute Myeloid Leukemia
  • San Francisco, California
  • +3 more
Jun 13, 2022

Melanoma, Solid Tumor Trial in Korea, Republic of, Spain, United States (DAY101, Pimasertib Hydrochloride)

Recruiting
  • Melanoma
  • Solid Tumor
  • Los Angeles, California
  • +13 more
Jul 27, 2022

Resistance-associated Mutations in Metastatic Lung Cancer

Recruiting
  • Lung Cancer
  • Liquid biopsy
  • Monza, MB, Italy
    Fondazione IRCCS San Gerardo dei Tintori
Oct 10, 2023

Tumor, Solid, Gastrointestinal Cancer Trial in San Francisco, Ann Arbor (Ulixertinib, Hydroxychloroquine)

Recruiting
  • Tumor, Solid
  • Gastrointestinal Cancer
  • Tucson, Arizona
  • +7 more
Jan 13, 2023

Advanced Malignant Solid Tumor, Recurrent Ependymal Tumor, Recurrent Ewing Sarcoma Trial in Puerto Rico, United States

Active, not recruiting
  • Advanced Malignant Solid Neoplasm
  • +35 more
  • Birmingham, Alabama
  • +108 more
Oct 19, 2022

Ovarian Tumors, Non-Small-Cell Lung Carcinoma, Melanoma Trial in Worldwide (LTT462)

Terminated
Has Results
  • Ovarian Neoplasms
  • +3 more
  • New York, New York
  • +6 more
Aug 15, 2019

Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic

Not yet recruiting
  • Acute Lymphoblastic Leukemia
  • +4 more
  • Utrecht, Netherlands
    Princess Máxima Center for Pediatric Oncology
Feb 20, 2023

Advanced Malignant Solid Tumor, Metastatic Malignant Solid Tumor, Refractory Malignant Solid Tumor Trial in Boston, Galveston,

Suspended
  • Advanced Malignant Solid Neoplasm
  • +4 more
  • Boston, Massachusetts
  • +2 more
Oct 5, 2022

Acute Lymphoblastic Leukemia, in Relapse, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent,

Not yet recruiting
  • Acute Lymphoblastic Leukemia, in Relapse
  • +4 more
  • Utrecht, Netherlands
    Princess Máxima Center for Pediatric Oncology
Dec 13, 2022

Advanced Malignant Tumor, ATM Gene Mutation, BRCA1 Gene Mutation Trial in Houston (Laboratory Biomarker Analysis,

Active, not recruiting
  • Advanced Malignant Neoplasm
  • +7 more
  • Laboratory Biomarker Analysis
  • +2 more
  • Houston, Texas
    M D Anderson Cancer Center
Feb 21, 2022

Proteus Syndrome, PIK3CA-Related Overgrowth Spectrum (PROS), Growth Disorders Trial (ARQ 092)

No longer available
  • Proteus Syndrome
  • +2 more
  • ARQ 092
  • (no location specified)
Jul 31, 2021

Castration-resistant Prostate Cancer, Metastasis Trial in France (Carboplatin)

Terminated
  • Castration-resistant Prostate Cancer
  • Metastasis
  • Caen, France
  • +3 more
Apr 28, 2021

Thyroid Cancer, Thyroid Cancer, Follicular, Papillary Thyroid Cancer Trial in United States (Trametinib, Dabrafenib, PDR001)

Recruiting
  • Thyroid Cancer
  • +6 more
  • Basking Ridge, New Jersey
  • +6 more
Jan 19, 2023

Locally Advanced Leiomyosarcoma, Metastatic Leiomyosarcoma, Stage III Retroperitoneal Sarcoma AJCC v8 Trial in Columbus

Not yet recruiting
  • Locally Advanced Leiomyosarcoma
  • +6 more
  • Niraparib Tosylate Monohydrate
  • Columbus, Ohio
    Ohio State University Comprehensive Cancer Center
Jul 25, 2022

Migraine Trial in Saint Louis (device, behavioral, diagnostic test, other)

Recruiting
  • Migraine
  • Thermal stimuli
  • +7 more
  • Saint Louis, Missouri
    Washington University School of Medicine
Feb 20, 2023